Endocrine Abstracts

Introduction: Acromegaly is caused by excessive growth hormone production and elevated IGF-1 levels. Annual incidence rates are reported to be between 0.2 and 1.1 cases/100 000 people, with a prevalence of 2.8–13.7 cases/100 000 people. Small numbers make it difficult to differentiate any differences between sex. A recent increase in the number of females diagnosed with acromegaly at our centre, voiced a need for peer and psychological support. It is known that acromegaly...

Type 1B pseudohypoparathyroidism is characterised by renal resistance to parathyroid hormone in the absence of other endocrine or physical abnormalities. We present a 36-year-old lady with pseudohypoparathyroidism diagnosed aged seven following seizures with hypocalcaemia, hyperphosphataemia, elevated alkaline phosphatase, elevated parathyroid hormone (PTH) at 700 pg/mL (<120) and no cyclic AMP response to bovine PTH. There was no family history or diagnostic phenotypic fe...